Many people think that diabetes is far away from them, but in fact it is terrifyingly close.According to statistics, the total number of diabetic patients in my country ranks first in the world, among whichThe prevalence rate among adults is approximately 11.6%。What is even more noteworthy is that nearly half of the adults in our country have abnormal blood sugar. If timely intervention is not performed, it is likely to cause many adverse consequences.Diabetes is a metabolic disease characterized by elevated blood sugar due to defects in insulin secretion and/or action.Normally, the pancreas releases insulin to help the body store and use sugar and fat from food. Diabetes results when the pancreas produces less insulin, or when the body becomes less sensitive to insulin.Diabetes can be divided intoType 1 diabetes, type 2 diabetes, gestational diabetes, special types of diabetes(In addition to the above three types, the general term for other diabetes).Typical symptoms of diabetes areThree more and one less:
Patients with type 2 diabetes often have no obvious symptoms in the early stages. As the disease progresses, patients may develop symptoms such as:Slow healing of wounds, pain or numbness in legs and feet, skin itching, weight loss, and vision loss after injuryWait.If you have the typical symptoms of three more and one less, and meet any of the following conditions, you already have diabetes:①Fasting blood glucose level >7.0mmol/L (126mg/dI)②Blood sugar >11.1mmol/L (200mg/dI) at any time of the day③Oral glucose tolerance test 2-hour blood glucose level >11.1mmol/L (200mg/dI)complications of diabetesDiabetes can cause chronic and acute complications. Acute complications include ketoacidosis and nonketotic hyperosmolar coma. Common chronic complications includeDiabetic retinopathy, diabetic nephropathy and diabetic foot。The relationship between gut microbiota and diabetesgut microbiota is also closely related to diabetes:
TreatGut classic case sharingMr. X’s anti-sugar journeyMr. X’s personalized Precision Microbiota Transplantation planIn August and October 2022, Mr. X underwent 2 courses of precisely matched microbiota transplantation. TreatGut customized the Precision Microbiota Transplantation plan for Mr.With the joint efforts of TreatGut and Mr. X, his health data, physical sensation, and quality of life have been greatly improved.Main transplant requirements:reverse sugarMedical history/symptoms:I have been suffering from diabetes for more than 20 years and have been taking insulin for more than 10 years, along with oral hypoglycemic drugs.Diagnosis:1. Type II diabetes 2. Moderate gut microbiota imbalance 3. HypertensionTreatGut five-dimensional model positioning:metabolic systemPersonalized plan and dietary guidance① 2 courses of treatment accurately matched microbiota transplantation120 capsules for the first course of treatment + 120 capsules for the second course of treatment② Online real-time VIP health management guidance service to help customers develop healthy eating patterns
Transplantation effectiveness evaluationAs can be seen from the figure below, the patient's gut microbiota score before transplantation was 40.5, which was a moderate imbalance. After the first course of transplantation, the score rose to 72.3, an increase of 78.5%. The patient's gut microbiota decreased from a moderate imbalance to a mild imbalance.The second course of treatment consolidated the efficacy and the score rose to 77.8.(1st course of treatment)(2nd course of treatment)gut microbiota related data:As you can see from the figure below, Mr. X’s gut microbiota-related data changes from before transplantation to after the second course of treatment.(Before transplantation → 1st course of treatment → 2nd course of treatment)High-risk diseases:Yes → Yes →NoneCore beneficial bacteria:Low → Normal →Rich(1st course of treatment)(2nd course of treatment）Disease-related risk index:After 2 courses of transplantation, Mr.The score of diabetes dropped from 69.23 to 30.26, and the risk dropped from medium to low.See the figure below for specific changes:(1st course of treatment）(2nd course of treatment）Comparison of somatosensory and physical examination dataOverall feedback after the first course of treatment:Increased flatulence (farts are abundant and smelly), but sleep, defecation, mental state, etc. are normal.
Overall feedback after the second course of treatment:The exhaustion is similar to the first course of treatment, but there is no odor, the blood pressure is more stable than before, and the overall mental state is good.After the first course of treatment, I stopped taking insulin and only took hypoglycemic drugs until now.
Physical examination data:[Physical examination data on May 26, 2022 (before transplantation)]Glycated hemoglobin:7.2 ↑(Reference value: 4.3-6.1)higher than reference valueFasting insulin: 12.6pmol/L ↓(Reference value: 17.8-173.0) Lower than the reference valueFasting C-peptide (E): 0.319nmol/L ↓(Reference value: 0.370-1.470) Lower than reference value[Physical examination data on November 9, 2022 (after the second course of treatment and transplantation)]After the second course of treatment, Mr. X's diabetes-related indicators tended to the reference values, and some indicators returned to normal.Glycated hemoglobin: 6.6 ↑(Reference value: 4.3-6.1) Close to the reference valueFasting insulin: 24pmol/L(Reference value: 17.8-173.0) Within the reference valueFasting C-peptide (E): 0.486 nmol/L(Reference value: 0.370-1.470) Within the reference valuePrecision Microbiota TransplantationIn China, microbiota transplantation has been used to treat diseases for more than 1,700 years. In 300-400 AD, Chinese medicine practitioner Ge Hong described in detail the use of fecal suspensions to treat serious illnesses such as food poisoning and severe diarrhea in his book "Emergency Prescriptions". In recent years, microbiota transplantation has been used in the treatment of more than 30 diseases at home and abroad.Precision Microbiota Transplantation(Precision Microbiota Transplantation, PMT) refers to passing the gut microbiota of healthy donors through an intelligent intestinal bacteria processing systemMade into suspension or capsule, adoptDonor-receptor matchingThe technology selects the optimal donor flora, transplants it into the patient's intestines, and rebuilds the normal functional gut microbiota to achieve the treatment of intestinal and extraintestinal diseases.TreatGut defines Precision Microbiota Transplantation from the following aspects,Leading the microbiota transplantation industry towards the 3.0 era.
